Journal: PLOS One
Article Title: 3D finite element models reveal regional fatty infiltration modulates tibialis anterior force generating capacity in FSHD
doi: 10.1371/journal.pone.0319881
Figure Lengend Snippet: Finite element model generation pipeline. The finite element model geometry development pipeline begins with muscle volume and central aponeurosis segmentations from MRIs, followed by 3D computer aided design (CAD) models of the TA and central aponeurosis. These volumes were then meshed into tetrahedrons for FE analysis. The muscle fascicles and central aponeurosis fibers were generated through Laplacian fluid flow simulation and the velocity vectors were mapped to the mesh. Lastly, the voxel-based fat fraction determined from the Dixon MRI was mapped to each element in the volume, allowing for anatomic representation of the fat infiltration pattern.
Article Snippet: The points were then used to define axial slice contours which were then lofted into the volumes of the TA and central aponeurosis (Autodesk Inventor 2024, San Francisco, CA, USA).
Techniques: Generated